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Understanding biology at the system level has gained much more interest recently due to the rapid development in genome sequencing and high-throughput measurements. Mathematical descriptions of biological systems are normally formalized using two different approaches. The deterministic method is very efficient at predicting the overall behavior of the system but ignores the inherent fluctuations and correlations at lower concentration. The stochastic method, on the other hand, captures the intrinsic randomness but is often mathematically intractable and computationally expensive.