CSc8540 Advanced Bioinformatics Algorithms

Table of Contents Flyer 1 Pevzner’s book Pevzner’s slides Human Haplotypes 2003 Human Shamir’s class Biostatistics class Statistics Mendelian Genetics Phasing paper with Clark’s method Epidemiology Phasing shotguns Population genetics sites: Gonçalo's Lectures General 1 General 2 HWE HWE deviation calc HapMap Tagging

LIST OF PROJECTS/Presentations ANNOUNCEMENTS/HOMEWORKS/ASSIGNMENTS Turning-in/grading policy: - Full grade = homework is received by e-mail by GLA before the class on the due date - No (zero-) grade = afterwards For extra-credit problems the grade is calculated as follows: - the number of points assigned is divided by the number of correct answers - credit is given only if the answer is turned in the beginning of the class on due date All questions on HW/Quiz grading should be addressed to GLA  email: 1. Homework 1. 2. Homework 2. 3. HW3: Let S be a set of haplotypes on m SNPs in which any two SNPs do not violate 4-gamete rule, i.e., S has been obtained without recombinations. Prove that S can have at most m+1 different haplotypes. 4.

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